5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TMCO6	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	TRIM7	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	HNRNPA1L2	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	CCR6	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	RP11-345J4.5	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	CRCP	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	OR1L3	CTRPv2	pan-cancer	AAC	-0.1	0.002
mRNA	SLC25A14	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	EEF1AKMT1	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	HIKESHI	CTRPv2	pan-cancer	AAC	-0.11	0.002

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