5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ERICH6	CTRPv2	pan-cancer	AAC	-0.11	0.0008
mRNA	COX10	CTRPv2	pan-cancer	AAC	0.12	0.0008
mRNA	PRF1	CTRPv2	pan-cancer	AAC	0.11	0.0008
mRNA	CCL13	CTRPv2	pan-cancer	AAC	0.11	0.0008
mRNA	NELFE	CTRPv2	pan-cancer	AAC	-0.11	0.0008
mRNA	RAB29	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	LARP6	CTRPv2	pan-cancer	AAC	-0.13	0.0009
mRNA	MBLAC1	CTRPv2	pan-cancer	AAC	-0.11	0.0009
mRNA	ZNF121	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	FAM167B	CTRPv2	pan-cancer	AAC	-0.13	0.0009

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