5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PTS	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	HLA-E	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	RABAC1	CTRPv2	pan-cancer	AAC	-0.12	0.0004
mRNA	TMEM260	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	MYBL1	CTRPv2	pan-cancer	AAC	-0.12	0.0004
mRNA	KRBOX4	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	PLG	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	RPL6	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	MLKL	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	RREB1	CTRPv2	pan-cancer	AAC	0.13	0.0004

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