5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MTFR1L	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	EEF1A1	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	LCP1	CTRPv2	pan-cancer	AAC	0.16	0.0003
mRNA	GIPR	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	RPL26	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	F12	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	CCR7	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	MAMDC4	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	TNFRSF12A	CTRPv2	pan-cancer	AAC	-0.15	0.0004
mRNA	RP11-849F2.7	CTRPv2	pan-cancer	AAC	0.13	0.0004

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