5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SNTA1	CTRPv2	pan-cancer	AAC	-0.13	0.0001
mRNA	DUSP16	CTRPv2	pan-cancer	AAC	0.13	0.0001
mRNA	KCNE5	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	HIST1H2BN	CTRPv2	pan-cancer	AAC	-0.13	0.0002
mRNA	RNF43	CTRPv2	pan-cancer	AAC	0.17	0.0002
mRNA	LYZ	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	HSD17B7	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	ABL2	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	OPHN1	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	EIF2S3	CTRPv2	pan-cancer	AAC	0.13	0.0002

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