5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NEK5	CTRPv2	pan-cancer	AAC	0.083	0.02
mRNA	CCL23	CTRPv2	pan-cancer	AAC	0.081	0.02
mRNA	OR56B4	CTRPv2	pan-cancer	AAC	-0.079	0.02
mRNA	MIA-RAB4B	CTRPv2	pan-cancer	AAC	-0.097	0.02
mRNA	RPS12	CTRPv2	pan-cancer	AAC	0.093	0.02
mRNA	PXN	CTRPv2	pan-cancer	AAC	-0.091	0.02
mRNA	RPL19	CTRPv2	pan-cancer	AAC	0.083	0.02
mRNA	OVOL1	CTRPv2	pan-cancer	AAC	0.097	0.02
mRNA	FAM58A	CTRPv2	pan-cancer	AAC	-0.084	0.02
mRNA	APOBEC3G	CTRPv2	pan-cancer	AAC	0.085	0.02

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