5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RSPH1	CTRPv2	pan-cancer	AAC	0.087	0.02
mRNA	ANXA7	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	GOLT1B	CTRPv2	pan-cancer	AAC	-0.083	0.02
mRNA	C19orf67	CTRPv2	pan-cancer	AAC	-0.08	0.02
mRNA	PRR21	CTRPv2	pan-cancer	AAC	-0.081	0.02
mRNA	FRS3	CTRPv2	pan-cancer	AAC	0.081	0.02
mRNA	FGD6	CTRPv2	pan-cancer	AAC	-0.089	0.02
mRNA	CNKSR1	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	GABARAPL1	CTRPv2	pan-cancer	AAC	-0.085	0.02
mRNA	VN1R1	CTRPv2	pan-cancer	AAC	-0.088	0.02

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