5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MRPL58	CTRPv2	pan-cancer	AAC	0.083	0.02
mRNA	ATP7A	CTRPv2	pan-cancer	AAC	-0.087	0.02
mRNA	RP11-371E8.4	CTRPv2	pan-cancer	AAC	-0.083	0.02
mRNA	ZNF285	CTRPv2	pan-cancer	AAC	-0.084	0.02
mRNA	EHD2	CTRPv2	pan-cancer	AAC	-0.091	0.02
mRNA	H3F3C	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	DYNAP	CTRPv2	pan-cancer	AAC	-0.079	0.02
mRNA	GNA11	CTRPv2	pan-cancer	AAC	-0.11	0.02
mRNA	FAM206A	CTRPv2	pan-cancer	AAC	0.088	0.02
mRNA	NDUFB3	CTRPv2	pan-cancer	AAC	-0.082	0.02

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