5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NFIL3	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	CCAR1	CTRPv2	pan-cancer	AAC	0.087	0.02
mRNA	ZFHX3	CTRPv2	pan-cancer	AAC	-0.09	0.02
mRNA	TBC1D7	CTRPv2	pan-cancer	AAC	-0.095	0.02
mRNA	KLHL17	CTRPv2	pan-cancer	AAC	0.083	0.02
mRNA	FAHD2B	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	IL13RA2	CTRPv2	pan-cancer	AAC	-0.081	0.02
mRNA	MS4A14	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	PINK1	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	EXOSC8	CTRPv2	pan-cancer	AAC	0.089	0.02

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