5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RHOXF2B	CTRPv2	pan-cancer	AAC	0.081	0.01
mRNA	CGRRF1	CTRPv2	pan-cancer	AAC	-0.087	0.01
mRNA	PDE7B	CTRPv2	pan-cancer	AAC	-0.082	0.01
mRNA	CRIPT	CTRPv2	pan-cancer	AAC	-0.084	0.01
mRNA	PTGDR	CTRPv2	pan-cancer	AAC	0.081	0.01
mRNA	DMRT1	CTRPv2	pan-cancer	AAC	0.08	0.01
mRNA	PGM2L1	CTRPv2	pan-cancer	AAC	-0.085	0.01
mRNA	SEMA4G	CTRPv2	pan-cancer	AAC	0.094	0.01
mRNA	MEIS1	CTRPv2	pan-cancer	AAC	0.093	0.01
mRNA	IFNAR1	CTRPv2	pan-cancer	AAC	-0.085	0.01

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