5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IFT80	CTRPv2	pan-cancer	AAC	-0.083	0.01
mRNA	TMEM51	CTRPv2	pan-cancer	AAC	-0.095	0.01
mRNA	RP11-290H9.2	CTRPv2	pan-cancer	AAC	-0.097	0.01
mRNA	TCF19	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	WDR49	CTRPv2	pan-cancer	AAC	0.082	0.01
mRNA	SLC51A	CTRPv2	pan-cancer	AAC	0.081	0.01
mRNA	PCSK1N	CTRPv2	pan-cancer	AAC	-0.087	0.01
mRNA	DKK3	CTRPv2	pan-cancer	AAC	-0.1	0.01
mRNA	SH3BGRL	CTRPv2	pan-cancer	AAC	-0.092	0.01
mRNA	RNF157	CTRPv2	pan-cancer	AAC	0.086	0.01

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