5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TMEM105	CTRPv2	pan-cancer	AAC	0.085	0.01
mRNA	PRKCA	CTRPv2	pan-cancer	AAC	-0.093	0.01
mRNA	RNF6	CTRPv2	pan-cancer	AAC	0.088	0.01
mRNA	DAP	CTRPv2	pan-cancer	AAC	-0.084	0.01
mRNA	FAM188A	CTRPv2	pan-cancer	AAC	-0.083	0.01
mRNA	DPH5	CTRPv2	pan-cancer	AAC	0.085	0.01
mRNA	AMELX	CTRPv2	pan-cancer	AAC	-0.081	0.01
mRNA	ABHD8	CTRPv2	pan-cancer	AAC	-0.085	0.01
mRNA	POFUT1	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	EMC1	CTRPv2	pan-cancer	AAC	-0.093	0.01

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