5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IL1R2	CTRPv2	pan-cancer	AAC	0.13	6e-05
mRNA	LRP8	CTRPv2	pan-cancer	AAC	0.14	6e-05
mRNA	CECR6	CTRPv2	pan-cancer	AAC	0.14	6e-05
mRNA	TMPRSS11F	CTRPv2	pan-cancer	AAC	0.13	6e-05
mRNA	BICD1	CTRPv2	pan-cancer	AAC	-0.14	6e-05
mRNA	PAAF1	CTRPv2	pan-cancer	AAC	-0.14	6e-05
mRNA	C1orf131	CTRPv2	pan-cancer	AAC	0.14	6e-05
mRNA	AC015688.3	CTRPv2	pan-cancer	AAC	0.15	6e-05
mRNA	RALGPS2	CTRPv2	pan-cancer	AAC	-0.13	6e-05
mRNA	SPNS3	CTRPv2	pan-cancer	AAC	0.14	6e-05

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