5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APOC2	CTRPv2	pan-cancer	AAC	0.14	5e-05
mRNA	CD163	CTRPv2	pan-cancer	AAC	0.13	5e-05
mRNA	PLD6	CTRPv2	pan-cancer	AAC	0.15	5e-05
mRNA	FMNL1	CTRPv2	pan-cancer	AAC	0.18	5e-05
mRNA	THUMPD2	CTRPv2	pan-cancer	AAC	0.14	5e-05
mRNA	ZNF599	CTRPv2	pan-cancer	AAC	-0.14	5e-05
mRNA	SQRDL	CTRPv2	pan-cancer	AAC	0.14	5e-05
mRNA	ZNF726	CTRPv2	pan-cancer	AAC	-0.15	5e-05
mRNA	ABCA13	CTRPv2	pan-cancer	AAC	0.13	6e-05
mRNA	KLF5	CTRPv2	pan-cancer	AAC	0.18	6e-05

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