5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ORAI2	CTRPv2	pan-cancer	AAC	-0.16	2e-05
mRNA	ZNF772	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	RPL13A	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	RPS8	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	BMT2	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	GPR35	CTRPv2	pan-cancer	AAC	0.17	2e-05
mRNA	CGREF1	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	GPCPD1	CTRPv2	pan-cancer	AAC	0.15	3e-05
mRNA	MEF2D	CTRPv2	pan-cancer	AAC	0.16	3e-05
mRNA	VEGFB	CTRPv2	pan-cancer	AAC	-0.15	3e-05

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