5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MPST	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	POLR1D	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	TRIM25	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	ATF4	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	PARVG	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	HAUS4	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	CCDC13	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	TARBP1	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	IFITM1	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	RP11-298I3.5	CTRPv2	pan-cancer	AAC	0.15	2e-05

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