5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PHYKPL	CTRPv2	pan-cancer	AAC	0.16	7e-06
mRNA	RPL29	CTRPv2	pan-cancer	AAC	0.18	7e-06
mRNA	CALU	CTRPv2	pan-cancer	AAC	-0.19	7e-06
mRNA	CHKB-CPT1B	CTRPv2	pan-cancer	AAC	0.17	8e-06
mRNA	LAD1	CTRPv2	pan-cancer	AAC	0.18	9e-06
mRNA	CCR2	CTRPv2	pan-cancer	AAC	0.15	9e-06
mRNA	PROK2	CTRPv2	pan-cancer	AAC	0.15	9e-06
mRNA	LTB4R	CTRPv2	pan-cancer	AAC	0.16	9e-06
mRNA	FAM127A	CTRPv2	pan-cancer	AAC	-0.19	1e-05
mRNA	RPL12	CTRPv2	pan-cancer	AAC	0.16	1e-05

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