5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CPT1B	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	IRF5	CTRPv2	pan-cancer	AAC	0.17	3e-06
mRNA	GPR84	CTRPv2	pan-cancer	AAC	0.16	3e-06
mRNA	FAM114A1	CTRPv2	pan-cancer	AAC	-0.19	3e-06
mRNA	IL26	CTRPv2	pan-cancer	AAC	0.15	3e-06
mRNA	HNRNPA1	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	CKMT1A	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	IRF2BP2	CTRPv2	pan-cancer	AAC	0.16	4e-06
mRNA	TMEM263	CTRPv2	pan-cancer	AAC	-0.17	4e-06
mRNA	ALPK1	CTRPv2	pan-cancer	AAC	0.16	4e-06

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