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GSK461364

GSK461364

Synonyms

Sources	Names Used
GRAY, CTRPv2	GSK461364
PharmacoGx	GSK461364

External IDs

Database	Identifier
Smiles:	CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N
Inchikey:	ZHJGWYRLJUCMRT-QGZVFWFLSA-N
Pubchem:	15983966

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to GSK461364

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRLH	CTRPv2	pan-cancer	AAC	-0.18	7e-09
mRNA	DUT	CTRPv2	pan-cancer	AAC	0.23	7e-09
mRNA	DNAJB2	CTRPv2	pan-cancer	AAC	-0.19	7e-09
mRNA	SRSF1	CTRPv2	pan-cancer	AAC	0.19	7e-09
mRNA	ORC2	CTRPv2	pan-cancer	AAC	0.19	7e-09
mRNA	DPH5	CTRPv2	pan-cancer	AAC	0.18	7e-09
mRNA	PPRC1	CTRPv2	pan-cancer	AAC	0.19	8e-09
mRNA	THRAP3	CTRPv2	pan-cancer	AAC	0.19	8e-09
mRNA	CHMP4B	CTRPv2	pan-cancer	AAC	-0.19	8e-09
mRNA	PAXBP1	CTRPv2	pan-cancer	AAC	0.19	9e-09

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