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GSK1120212

Synonyms

SourcesNames Used
GDSC1000Trametinib
GRAYGSK1120212
CTRPv2trametinib
PharmacoGx GSK1120212

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Inchikey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Pubchem: 11707110

FDA Approval Status

Approved
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Top molecular features associated with response to GSK1120212


Feature TypeStandardized
Nominal ANOVA
mRNA LPCAT2 CTRPv2 pan-cancer AAC 0.25 1e-06
mRNA XRCC3 CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA UPF2 CTRPv2 pan-cancer AAC -0.26 1e-06
mRNA ZNF253 CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA ETS1 CTRPv2 pan-cancer AAC -0.24 1e-06
mRNA PRPS1 CTRPv2 pan-cancer AAC -0.26 1e-06
mRNA SLC35B2 CTRPv2 pan-cancer AAC 0.25 1e-06
mRNA ESPL1 CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA TIMELESS CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA USP13 CTRPv2 pan-cancer AAC -0.24 1e-06
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