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GSK1120212

Synonyms

SourcesNames Used
GDSC1000Trametinib
GRAYGSK1120212
CTRPv2trametinib
PharmacoGx GSK1120212

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Inchikey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Pubchem: 11707110

FDA Approval Status

Approved
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Top molecular features associated with response to GSK1120212


Feature TypeStandardized
Nominal ANOVA
mRNA FAM65B CTRPv2 pan-cancer AAC -0.31 6e-08
mRNA CKAP5 CTRPv2 pan-cancer AAC -0.27 7e-08
mRNA IRF2BP2 CTRPv2 pan-cancer AAC 0.26 7e-08
mRNA TCF4 CTRPv2 pan-cancer AAC -0.3 7e-08
mRNA PYCARD CTRPv2 pan-cancer AAC 0.27 8e-08
mRNA OSBPL5 CTRPv2 pan-cancer AAC 0.27 8e-08
mRNA C10orf90 CTRPv2 pan-cancer AAC 0.31 8e-08
mRNA AL078584.1 CTRPv2 pan-cancer AAC -0.31 8e-08
mRNA RP4-635E18.9 CTRPv2 pan-cancer AAC -0.27 9e-08
mRNA USP49 CTRPv2 pan-cancer AAC -0.29 9e-08
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