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GSK1120212

Synonyms

SourcesNames Used
GDSC1000Trametinib
GRAYGSK1120212
CTRPv2trametinib
PharmacoGx GSK1120212

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Inchikey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Pubchem: 11707110

FDA Approval Status

Approved
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Top molecular features associated with response to GSK1120212


Feature TypeStandardized
Nominal ANOVA
mRNA RTN4IP1 CTRPv2 pan-cancer AAC -0.15 0.002
mRNA KNTC1 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA GLB1L CTRPv2 pan-cancer AAC 0.16 0.002
mRNA TSC22D1 CTRPv2 pan-cancer AAC 0.16 0.002
mRNA NRDE2 CTRPv2 pan-cancer AAC -0.15 0.002
mRNA ZNF695 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA HRH3 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA CLCN6 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA FBXW7 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA MED22 CTRPv2 pan-cancer AAC -0.15 0.002
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