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GSK1120212

Synonyms

SourcesNames Used
GDSC1000Trametinib
GRAYGSK1120212
CTRPv2trametinib
PharmacoGx GSK1120212

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Inchikey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Pubchem: 11707110

FDA Approval Status

Approved
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Top molecular features associated with response to GSK1120212


Feature TypeStandardized
Nominal ANOVA
mRNA ATOX1 CTRPv2 pan-cancer AAC 0.18 0.002
mRNA CTDSPL2 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA MYLK3 CTRPv2 pan-cancer AAC -0.15 0.002
mRNA C20orf196 CTRPv2 pan-cancer AAC -0.19 0.002
mRNA NDFIP2 CTRPv2 pan-cancer AAC 0.17 0.002
mRNA ZNF543 CTRPv2 pan-cancer AAC -0.16 0.002
mRNA ABHD17C CTRPv2 pan-cancer AAC 0.17 0.002
mRNA EDA2R CTRPv2 pan-cancer AAC 0.17 0.002
mRNA SPNS3 CTRPv2 pan-cancer AAC 0.15 0.002
mRNA GHRL CTRPv2 pan-cancer AAC 0.15 0.002
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