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GSK1120212

Synonyms

SourcesNames Used
GDSC1000Trametinib
GRAYGSK1120212
CTRPv2trametinib
PharmacoGx GSK1120212

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Inchikey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Pubchem: 11707110

FDA Approval Status

Approved
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Top molecular features associated with response to GSK1120212


Feature TypeStandardized
Nominal ANOVA
mRNA LILRA1 CTRPv2 pan-cancer AAC 0.24 7e-07
mRNA ROPN1 CTRPv2 pan-cancer AAC 0.28 7e-07
mRNA TRIM51 CTRPv2 pan-cancer AAC 0.26 7e-07
mRNA SSR4 CTRPv2 pan-cancer AAC 0.23 7e-07
mRNA SSH1 CTRPv2 pan-cancer AAC 0.31 7e-07
mRNA FUT4 CTRPv2 pan-cancer AAC 0.26 8e-07
mRNA MYO1F CTRPv2 pan-cancer AAC 0.26 8e-07
mRNA SIRPB2 CTRPv2 pan-cancer AAC 0.23 8e-07
mRNA NLRP3 CTRPv2 pan-cancer AAC 0.23 8e-07
mRNA LRPAP1 CTRPv2 pan-cancer AAC 0.24 8e-07
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