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Vandetanib

Synonyms

SourcesNames Used
CCLE, FIMMVandetanib
CTRPv2vandetanib
PharmacoGx Vandetanib

External IDs

DatabaseIdentifier
Smiles: CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
Inchikey: UHTHHESEBZOYNR-UHFFFAOYSA-N
Pubchem: 3081361

Annotated Targets

SRC, TEK, EGFR, EPHA1, EPHA10, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, EPHB6, ERBB2, ERBB3, ERBB4, FLT1, FLT4, KDR, PTK6, RET, VEGFA

FDA Approval Status

Approved
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Top molecular features associated with response to Vandetanib


Feature TypeStandardized
Nominal ANOVA
mRNA CAMSAP3 CCLE pan-cancer AAC 0.16 0.005
mRNA EHMT1 CCLE pan-cancer AAC 0.13 0.005
mRNA ZNF182 CCLE pan-cancer AAC -0.14 0.005
mRNA CLCF1 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA SLC39A11 CCLE pan-cancer AAC 0.14 0.005
mRNA RASSF10 CCLE pan-cancer AAC 0.14 0.005
mRNA IMPA1 CCLE pan-cancer AAC -0.14 0.005
mRNA CD99L2 CCLE pan-cancer AAC -0.14 0.005
mRNA ORAI2 CCLE pan-cancer AAC -0.15 0.005
mRNA FOXN4 CTRPv2 pan-cancer AAC -0.1 0.005
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