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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA IKZF3 CCLE pan-cancer AAC -0.23 0.0002
mRNA GNRH2 CCLE pan-cancer AAC -0.23 1e-06
mRNA DNAAF1 CCLE pan-cancer AAC -0.23 3e-06
mRNA BSN CCLE pan-cancer AAC -0.23 6e-06
mRNA RNF32 CCLE pan-cancer AAC -0.23 9e-06
mRNA SNX22 CCLE pan-cancer AAC -0.23 3e-05
mRNA WBP2NL CCLE pan-cancer AAC -0.23 7e-06
mRNA BFSP2 CCLE pan-cancer AAC -0.23 4e-05
mRNA PNPLA8 CCLE pan-cancer AAC -0.22 4e-06
mRNA FAM214A CCLE pan-cancer AAC -0.22 5e-05
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