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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA C2CD4B CCLE pan-cancer AAC -0.13 0.006
mRNA GPD1 CCLE pan-cancer AAC -0.14 0.006
mRNA CTSB CCLE pan-cancer AAC 0.15 0.006
mRNA SEC61B CTRPv2 pan-cancer AAC -0.11 0.006
mRNA FBN1 FIMM pan-cancer AAC 0.45 0.006
mRNA EBF1 CCLE pan-cancer AAC -0.15 0.006
mRNA STT3B CCLE pan-cancer AAC 0.14 0.006
mRNA GABRR2 CTRPv2 pan-cancer AAC -0.12 0.006
mRNA MMAB CCLE pan-cancer AAC -0.14 0.006
mRNA FRAT2 FIMM pan-cancer AAC -0.5 0.006
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