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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA FREM2 CTRPv2 pan-cancer AAC 0.18 8e-06
mRNA FAM69B CTRPv2 pan-cancer AAC 0.18 8e-06
mRNA PNCK CCLE pan-cancer AAC -0.22 9e-06
mRNA RNF32 CCLE pan-cancer AAC -0.23 9e-06
mRNA TMX1 CCLE pan-cancer AAC 0.22 1e-05
mRNA HSH2D CTRPv2 pan-cancer AAC 0.21 1e-05
mRNA GPSM1 CTRPv2 pan-cancer AAC 0.2 1e-05
mRNA C1orf174 CCLE pan-cancer AAC 0.21 1e-05
mRNA SLC23A2 CTRPv2 pan-cancer AAC 0.19 1e-05
mRNA TNFRSF1A CCLE pan-cancer AAC 0.25 1e-05
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