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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA EVA1B FIMM pan-cancer AAC 0.62 6e-05
mRNA RGS6 CCLE pan-cancer AAC -0.2 6e-05
mRNA L3MBTL3 CTRPv2 pan-cancer AAC 0.17 6e-05
mRNA TXN CCLE pan-cancer AAC 0.21 6e-05
mRNA INS CTRPv2 pan-cancer AAC 0.17 6e-05
mRNA WNK2 CCLE pan-cancer AAC -0.2 6e-05
mRNA CD48 CCLE pan-cancer AAC -0.29 6e-05
mRNA TMEM98 CTRPv2 pan-cancer AAC 0.18 6e-05
mRNA GOLGA8M CTRPv2 pan-cancer AAC 0.16 6e-05
mRNA MED8 CTRPv2 pan-cancer AAC -0.17 6e-05
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