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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA DRAM1 CCLE pan-cancer AAC 0.22 5e-05
mRNA FAM214A CCLE pan-cancer AAC -0.22 5e-05
mRNA NOP10 CCLE pan-cancer AAC 0.19 5e-05
mRNA ACTN1 CCLE pan-cancer AAC 0.25 5e-05
mRNA CD22 CCLE pan-cancer AAC -0.21 5e-05
mRNA ATPIF1 CTRPv2 pan-cancer AAC -0.17 5e-05
mRNA SHANK1 CTRPv2 pan-cancer AAC 0.17 6e-05
mRNA THAP2 CTRPv2 pan-cancer AAC -0.17 6e-05
mRNA RPS6KA1 CCLE pan-cancer AAC 0.22 6e-05
mRNA GNG2 CTRPv2 pan-cancer AAC 0.18 6e-05
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