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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA BACH2 CCLE pan-cancer AAC -0.21 0.0001
mRNA ARHGAP18 CCLE pan-cancer AAC 0.2 0.0001
mRNA FOSL1 CCLE pan-cancer AAC 0.23 0.0001
mRNA KCNJ1 CCLE pan-cancer AAC -0.19 0.0001
mRNA SDK2 CCLE pan-cancer AAC -0.18 0.0001
mRNA BLZF1 CTRPv2 pan-cancer AAC -0.17 0.0001
mRNA CCAR2 CTRPv2 pan-cancer AAC 0.17 0.0001
mRNA OTOL1 CTRPv2 pan-cancer AAC 0.15 0.0001
mRNA ALDH1L2 CTRPv2 pan-cancer AAC -0.15 0.0001
mRNA UNC13B CTRPv2 pan-cancer AAC -0.16 0.0001
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