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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA LATS2 CCLE pan-cancer AAC 0.21 9e-05
mRNA GGT5 CTRPv2 pan-cancer AAC 0.15 9e-05
mRNA VPS26A CCLE pan-cancer AAC 0.21 9e-05
mRNA RAD54L2 CTRPv2 pan-cancer AAC 0.19 9e-05
mRNA CADPS CCLE pan-cancer AAC -0.2 9e-05
mRNA ENAM CCLE pan-cancer AAC -0.19 9e-05
mRNA GOLGA8O CTRPv2 pan-cancer AAC 0.16 9e-05
mRNA PLAU CCLE pan-cancer AAC 0.23 9e-05
mRNA DEFA5 CTRPv2 pan-cancer AAC 0.16 9e-05
mRNA HMCES CCLE pan-cancer AAC -0.19 9e-05
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