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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA JTB CCLE pan-cancer AAC -0.21 8e-05
mRNA DAPL1 CCLE pan-cancer AAC -0.18 8e-05
mRNA CRTC3 CCLE pan-cancer AAC 0.19 8e-05
mRNA GIT1 CTRPv2 pan-cancer AAC 0.16 8e-05
mRNA CSF2RA CCLE pan-cancer AAC 0.19 8e-05
mRNA KSR1 CTRPv2 pan-cancer AAC 0.16 8e-05
mRNA ABHD11 CCLE pan-cancer AAC -0.22 8e-05
mRNA KCNN3 CTRPv2 pan-cancer AAC -0.17 8e-05
mRNA TNFRSF17 CCLE pan-cancer AAC -0.24 8e-05
mRNA CFD CCLE pan-cancer AAC 0.2 8e-05
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