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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF225 CCLE pan-cancer AAC 0.2 7e-05
mRNA DNAJC30 CCLE pan-cancer AAC -0.19 7e-05
mRNA ZNF549 CCLE pan-cancer AAC 0.2 7e-05
mRNA TCF7L2 CCLE pan-cancer AAC 0.28 7e-05
mRNA MLKL CCLE pan-cancer AAC 0.2 7e-05
mRNA ETV6 CTRPv2 pan-cancer AAC 0.17 7e-05
mRNA CD101 CTRPv2 pan-cancer AAC 0.16 8e-05
mRNA TECTA CCLE pan-cancer AAC -0.19 8e-05
mRNA PRKRIP1 CCLE pan-cancer AAC -0.19 8e-05
mRNA PGAP1 CTRPv2 pan-cancer AAC 0.17 8e-05
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