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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA MCU CCLE pan-cancer AAC 0.23 2e-05
mRNA CHRNB2 CCLE pan-cancer AAC -0.21 2e-05
mRNA CA11 CTRPv2 pan-cancer AAC 0.18 2e-05
mRNA RTF1 CCLE pan-cancer AAC 0.22 2e-05
mRNA EVA1B CCLE pan-cancer AAC 0.21 2e-05
mRNA HAL CTRPv2 pan-cancer AAC 0.17 2e-05
mRNA GRIP2 CTRPv2 pan-cancer AAC 0.17 2e-05
mRNA TEAD4 CCLE pan-cancer AAC 0.26 2e-05
mRNA NKD1 CTRPv2 pan-cancer AAC 0.17 3e-05
mRNA GANC CCLE pan-cancer AAC 0.21 3e-05
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