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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA SUSD1 CCLE pan-cancer AAC 0.14 0.006
mRNA P2RX3 CCLE pan-cancer AAC -0.14 0.006
mRNA MSANTD2 CTRPv2 pan-cancer AAC 0.11 0.006
mRNA APLP2 CCLE pan-cancer AAC 0.15 0.006
mRNA ACOX2 CCLE pan-cancer AAC 0.14 0.006
mRNA SIPA1 CTRPv2 pan-cancer AAC 0.13 0.006
mRNA ECHDC2 CCLE pan-cancer AAC 0.16 0.006
mRNA LCP2 CTRPv2 pan-cancer AAC 0.13 0.006
mRNA DHRS7C CCLE pan-cancer AAC -0.13 0.006
mRNA ARHGEF19 CCLE pan-cancer AAC 0.15 0.006
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