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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA KIAA1456 CTRPv2 pan-cancer AAC 0.12 0.006
mRNA GNG12 FIMM pan-cancer AAC 0.88 0.006
mRNA ALX4 CCLE pan-cancer AAC -0.13 0.006
mRNA AGPAT5 CTRPv2 pan-cancer AAC 0.12 0.006
mRNA PLXNB1 CTRPv2 pan-cancer AAC 0.13 0.006
mRNA PRB4 CCLE pan-cancer AAC -0.13 0.006
mRNA NPC1L1 CCLE pan-cancer AAC -0.14 0.006
mRNA PANX2 CCLE pan-cancer AAC -0.14 0.006
mRNA RUNX1T1 CCLE pan-cancer AAC -0.14 0.006
mRNA PPARGC1A CCLE pan-cancer AAC -0.13 0.006
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