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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA GNB4 CCLE pan-cancer AAC 0.28 4e-07
mRNA NANOS3 CTRPv2 pan-cancer AAC 0.21 4e-07
mRNA FYB CCLE pan-cancer AAC 0.25 4e-07
mRNA NEDD4 CCLE pan-cancer AAC 0.27 5e-07
mRNA ARHGAP33 CCLE pan-cancer AAC -0.26 5e-07
mRNA ANXA1 CCLE pan-cancer AAC 0.29 7e-07
mRNA XKR6 CCLE pan-cancer AAC -0.26 7e-07
mRNA TSPO CCLE pan-cancer AAC 0.26 7e-07
mRNA EIF2AK4 CCLE pan-cancer AAC 0.25 8e-07
mRNA SFPQ CTRPv2 pan-cancer AAC 0.22 8e-07
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