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L-685458

Synonyms

SourcesNames Used
CCLE, CTRPv2L-685458
PharmacoGx L-685458

External IDs

DatabaseIdentifier
Smiles: CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OC(C)(C)C)O
Inchikey: MURCDOXDAHPNRQ-ZJKZPDEISA-N
Pubchem: 5479543

Annotated Targets

APH1A, NCSTN, PSEN1, PSENEN

FDA Approval Status

Not Approved
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Top molecular features associated with response to L-685458


Feature TypeStandardized
Nominal ANOVA
mRNA GALNT8 CTRPv2 pan-cancer AAC 0.19 5e-07
mRNA KIAA0922 CTRPv2 pan-cancer AAC 0.21 9e-07
mRNA OMP CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA DLEC1 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA ZNF107 CTRPv2 pan-cancer AAC 0.2 1e-06
mRNA CYP2J2 CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA ADAMTS6 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA PBRM1 CCLE pan-cancer AAC 0.26 1e-06
mRNA MMP9 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA HNRNPH1 CCLE pan-cancer AAC 0.23 2e-06
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