PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EVPL	CCLE	pan-cancer	AAC	0.26	2e-06
mRNA	RRAGD	CTRPv2	pan-cancer	AAC	-0.18	2e-06
mRNA	LPAR5	CTRPv2	pan-cancer	AAC	0.19	2e-06
mRNA	ZNF134	CCLE	pan-cancer	AAC	0.23	2e-06
mRNA	KEL	CTRPv2	pan-cancer	AAC	0.17	2e-06
mRNA	ZNF81	CTRPv2	pan-cancer	AAC	-0.17	3e-06
mRNA	TMEM265	CTRPv2	pan-cancer	AAC	0.19	3e-06
mRNA	GRAP2	CCLE	pan-cancer	AAC	0.23	3e-06
mRNA	TCEB3	CTRPv2	pan-cancer	AAC	-0.18	3e-06
mRNA	RPL7A	CTRPv2	pan-cancer	AAC	0.18	3e-06