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AZD0530

AZD0530

Synonyms

Sources	Names Used
CCLE	AZD0530
GDSC1000, FIMM	Saracatinib
CTRPv2	saracatinib
PharmacoGx	AZD0530

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SMPDL3B	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	CLDN23	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	ENO2	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	C1orf56	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	HNF1B	CTRPv2	pan-cancer	AAC	0.16	0.0004
mRNA	GATC	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	CXXC4	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	PTPRK	CTRPv2	pan-cancer	AAC	0.15	0.0004
mRNA	ASF1B	CTRPv2	pan-cancer	AAC	-0.14	0.0004
mRNA	VASP	CCLE	pan-cancer	AAC	0.17	0.0004

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