PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APLP2	CCLE	pan-cancer	AAC	0.19	0.0003
mRNA	DSC2	CCLE	pan-cancer	AAC	0.2	0.0003
mRNA	NTN3	CTRPv2	pan-cancer	AAC	-0.14	0.0003
mRNA	LSR	CCLE	pan-cancer	AAC	0.22	0.0003
mRNA	FASTKD1	CTRPv2	pan-cancer	AAC	-0.15	0.0003
mRNA	EEF1G	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	ZNF606	CCLE	pan-cancer	AAC	0.18	0.0003
mRNA	CADM1	CTRPv2	pan-cancer	AAC	-0.14	0.0003
mRNA	COPZ1	CCLE	pan-cancer	AAC	-0.17	0.0003
mRNA	GBP3	CTRPv2	pan-cancer	AAC	0.14	0.0003