PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACSF2	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ACSM1	CTRPv2	pan-cancer	AAC	0.22	7e-10
mRNA	ACSM3	CTRPv2	pan-cancer	AAC	0.15	3e-05
mRNA	ACTB	CCLE	pan-cancer	AAC	0.15	0.0009
mRNA	ACTL6B	CTRPv2	pan-cancer	AAC	-0.17	1e-05
mRNA	ACTN1	CCLE	pan-cancer	AAC	0.18	0.002
mRNA	ACTN4	CCLE	pan-cancer	AAC	0.15	0.003
mRNA	ACTR3B	CTRPv2	pan-cancer	AAC	-0.13	0.0008
mRNA	ACYP1	CCLE	pan-cancer	AAC	-0.17	0.0004
mRNA	ACYP1	CTRPv2	pan-cancer	AAC	-0.13	0.0005