PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C1orf122	CCLE	pan-cancer	AAC	-0.2	0.0001
mRNA	MBTPS2	CCLE	pan-cancer	AAC	-0.2	5e-05
mRNA	PRDX4	CCLE	pan-cancer	AAC	-0.2	6e-05
mRNA	PTS	CCLE	pan-cancer	AAC	-0.2	0.0002
mRNA	EML6	CCLE	pan-cancer	AAC	-0.2	0.0001
mRNA	PYGO2	CTRPv2	pan-cancer	AAC	-0.2	1e-07
mRNA	FLAD1	CTRPv2	pan-cancer	AAC	-0.2	3e-07
mRNA	NABP2	CTRPv2	pan-cancer	AAC	-0.19	9e-08
mRNA	FSD1	CTRPv2	pan-cancer	AAC	-0.19	8e-06
mRNA	NDUFB11	CTRPv2	pan-cancer	AAC	-0.19	1e-07