PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	STON2	CCLE	pan-cancer	AAC	0.21	9e-06
mRNA	SLC44A2	CCLE	pan-cancer	AAC	0.23	1e-05
mRNA	EIF1AX	CCLE	pan-cancer	AAC	-0.21	1e-05
mRNA	ENPP1	CCLE	pan-cancer	AAC	-0.22	2e-05
mRNA	CTSH	CCLE	pan-cancer	AAC	0.21	2e-05
mRNA	TMEM5	CCLE	pan-cancer	AAC	-0.2	2e-05
mRNA	KCNK5	CCLE	pan-cancer	AAC	0.22	2e-05
mRNA	ITGB6	CCLE	pan-cancer	AAC	0.23	2e-05
mRNA	RREB1	CCLE	pan-cancer	AAC	0.21	2e-05
mRNA	GJB3	CCLE	pan-cancer	AAC	0.25	2e-05