PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EIF1AX	CCLE	pan-cancer	AAC	-0.21	1e-05
mRNA	POLR3GL	CCLE	pan-cancer	AAC	-0.21	9e-05
mRNA	TMEM5	CCLE	pan-cancer	AAC	-0.2	2e-05
mRNA	SEPT3	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	SUV39H1	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	NXPE3	CCLE	pan-cancer	AAC	-0.2	0.0001
mRNA	RAB39A	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	HLA-DPA1	CCLE	pan-cancer	AAC	-0.2	0.001
mRNA	TECPR1	CTRPv2	pan-cancer	AAC	-0.2	1e-07
mRNA	CLK2	CTRPv2	pan-cancer	AAC	-0.2	2e-06