PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF81	CTRPv2	pan-cancer	AAC	-0.17	3e-06
mRNA	ZNF81	CCLE	pan-cancer	AAC	-0.14	0.002
mRNA	ZNF823	CCLE	pan-cancer	AAC	0.17	0.0006
mRNA	ZNF91	CCLE	pan-cancer	AAC	0.14	0.003
mRNA	ZP1	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	ZSCAN18	CCLE	pan-cancer	AAC	0.21	3e-05
mRNA	ZSCAN31	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	ZSCAN4	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ZSWIM5	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	ZYG11B	CTRPv2	pan-cancer	AAC	-0.12	0.002