PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MICALL1	CCLE	pan-cancer	AAC	0.16	0.002
mRNA	MRPL34	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	NAP1L3	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	IQCA1	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	PREP	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	CDH1	CTRPv2	pan-cancer	AAC	0.14	0.002
mRNA	TMEM263	CCLE	pan-cancer	AAC	-0.16	0.002
mRNA	FYB	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	ZYG11B	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	MAP3K12	CCLE	pan-cancer	AAC	-0.15	0.002