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AZD0530

AZD0530

Synonyms

Sources	Names Used
CCLE	AZD0530
GDSC1000, FIMM	Saracatinib
CTRPv2	saracatinib
PharmacoGx	AZD0530

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SLC39A2	CCLE	pan-cancer	AAC	0.18	0.0001
mRNA	FCHO2	CTRPv2	pan-cancer	AAC	0.16	0.0001
mRNA	CDK5R1	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	ZFYVE21	CTRPv2	pan-cancer	AAC	0.16	0.0001
mRNA	RAB11FIP1	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CXorf57	CCLE	pan-cancer	AAC	-0.18	0.0001
mRNA	LIX1L	CTRPv2	pan-cancer	AAC	-0.17	0.0001
mRNA	UPF3A	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	MRPL24	CCLE	pan-cancer	AAC	-0.18	0.0001
mRNA	PTPDC1	CCLE	pan-cancer	AAC	-0.19	0.0001

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