PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ENSA	CTRPv2	pan-cancer	AAC	-0.15	9e-05
mRNA	KIAA1522	CCLE	pan-cancer	AAC	0.26	9e-05
mRNA	LPAR2	CCLE	pan-cancer	AAC	0.21	9e-05
mRNA	POLR3GL	CCLE	pan-cancer	AAC	-0.21	9e-05
mRNA	GTF3A	CTRPv2	pan-cancer	AAC	-0.16	9e-05
mRNA	NHLRC4	CTRPv2	pan-cancer	AAC	0.16	9e-05
mRNA	SEMG2	CCLE	pan-cancer	AAC	-0.18	9e-05
mRNA	RPL7	CTRPv2	pan-cancer	AAC	0.15	9e-05
mRNA	YBX3	CTRPv2	pan-cancer	AAC	0.15	9e-05
mRNA	CCDC6	CCLE	pan-cancer	AAC	0.2	9e-05